JAK/STAT INHIBITION NORMALIZES LIPID COMPOSITION IN 3D HUMAN EPIDERMAL EQUIVALENTS CHALLENGED WITH TH2 CYTOKINES

JAK/STAT Inhibition Normalizes Lipid Composition in 3D Human Epidermal Equivalents Challenged with Th2 Cytokines

Derangement of the epidermal barrier lipids and dysregulated immune responses are key pathogenic features of atopic dermatitis (AD).The seattle seahawks socks Th2-type cytokines interleukin IL-4 and IL-13 play a prominent role in AD by activating the Janus Kinase/Signal Transduction and Activator of Transcription (JAK/STAT) intracellular signaling

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Processes Underlying the Relation between Cognitive Ability and Curiosity with Academic Performance: A Mediation Analysis for Epistemic Behavior in a Five-Year Longitudinal Study

Cognitive ability and curiosity are significant predictors of academic achievement; yet the processes underlying these relations are not well understood.I drew on ideas from the environmental enrichment hypothesis and the differential preservation quest fryer hypothesis and hypothesized that epistemic behavior acts as a mediator.Longitudinal data w

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